   
Indications:
For the temporary relief of symptoms of osteoarthritis including mild to
moderate pain, articular stiffness and inflammation.
Contraindications:
Administration should be avoided in cases of known hypersensitivity to
Rhus toxicodendron.
Composition:
Tablets:
Each 300 mg tablet contains:
Silicea 6X
(calf cramps;
sciatica; weakness of ligaments)
3 mg;
Arnica montana, radix 1X
(soreness of back and limbs; rheumatism)
0.6 mg;
Rhus toxicodendron 1X
(rheumatic pain in tendons and ligaments, better with motion) 0.54 mg;
Sulphur 6X
(rheumatic shoulder pain; rheumatic gout; stiffness of
knees and ankles)
0.54 mg;
Sanguinaria canadensis 3X
(neuralgic,
rheumatic pain of joints and muscles)
0.45 mg;
Cartilago suis 4X
(arthritis; coxitis)
0.3 mg;
Embryo totalis suis 4X
(revitalization)
0.3 mg;
Funiculus
umbilicalis suis 4X
(support of connective tissue)
0.3 mg;
Placenta
suis 4X
(circulatory disturbances)
0.3 mg;
Dulcamara 2X
(paralyzed limbs; rheumatism after skin eruptions)
0.15 mg;
Symphytum
officinale 8X
(soreness of periostium; neuralgia of knee),
0.15 mg;
Coenzyme A 6X
(coenzyme for transacetylation)
0.03 mg;
α-Lipoicum
acidum 6X
(coenzyme in decomposition of pyruvic acid)
0.03 mg;
Nadidum 6X
(stimulation of end oxidation in respiratory chain)
0.03 mg;
Natrum oxalaceticum 6X
(sensitivity to dampness and wind)
0.03 mg;
in a lactose base.
Oral vials:
Each 100 ml contains:
Arnica montana, radix 4X
10 ml;
Rhus toxicodendron 2X,
Dulcamara 3X,
Symphytum officinale 6X
0.5 ml each;
Sulphur 6X
0.18 ml;
Sanguinaria canadensis 4X
0.15 ml;
Cartilago suis 6X,
Embryo totalis suis 6X,
Funiculus umbilicalis suis 6X,
Placenta suis 6X,
Coenzyme A 8X,
Nadidum 8X,
Natrum oxalaceticum 8X,
α-Lipoicum acidum 8X
0.1 ml each
in an isotonic sodium chloride solution base.
Ointment:
Silicea 6X 1.000 g;
Symphytum officinale 8X 0.750g;
Arnica montana, radix 2X 0.30 g;
Rhus toxicodendron 2X 0.270 g;
Sulphur 6X 0.270 g;
Sanguinaria canadensis 2X 0.225 g;
Dulcamara 2X 0.075 g;
Coenzyme A 6X,
α-Lipoicum acidum 6X,
Nadidum 6X,
Natrum oxalaceticum 6X 0.010 g each;
Cartilago suis 2X,
Embryo totalis suis 2X,
Funiculus umbilicalis suis 2X,
Placenta suis 2X 0.001 g each.
Inactive Ingredients:
Purified water, paraffin, white petrolatum, ethanol and cetylstearyl
alcohol.
Ointment: In rare cases, hypersensitivity reactions to the preservative
contained in the ointment may arise.
Interactions with other medication: None known.
Dosage:
Tablets:
Adults and children above 6 years:
1 tablet sublingually or dissolved completely in mouth 3 times daily or
as directed by a physician.
Infants and children to 6 years:
1/2 the adult dosage.
Oral vials:
Adults:
In general, 1 vial 1-3 times daily.
Children ages 2 to 6 receive 1/2 the adult dosage.
Note:
Unused portion of open vials should be discarded.
Not for injection.
Ointment: In general, apply in the morning and evening
to the affected areas, rubbing in gently.
If appropriate, also apply an ointment dressing.
Tablets: Bottle containing 100 tablets.
Oral vials: Pack containing 10 vials of 2.0 ml.
Ointment: Tube containing 50 g of ointment.
Pharmacological and
clinical notes
Constituents Indications
Cartilago (cartilage)
Arthrosis deformans, coxitis, periarthritis humero-scapularis
Funiculus umbilicalis (Wharton's jelly, (umbilical cord)
Damage to connective tissues, circulatory disorders
Embryo (embryo)
For revitalization in the cellular phases
Placenta (placenta)
Circulatory disturbances, pernios
Rhus toxicodendron (poison ivy)
Rheumatism and neuralgia, worse in cold, wet weather; polyarthritis, diseases of the
mucosa and connective tissues
Arnica (mountain arnica)
To stimulate the healing of wounds, rheumatism,
injuries arising from falls, blows or contusions;
pains in the back and limbs
Dulcamara (bittersweet)
Remedy to counteract the effects of wet weather sensation of having caught a chill,
rheumatic disorders
Symphytum (comfrey)
Injuries to the tendons, ligaments and periosteum; acts on the joints in general,
neuralgia of the knee
Sanguinaria (turmeric)
Neuralgic and rheumatoid pains of the joints and muscles
Sulfur (sulphur)
Reagent in all chronic diseases; cellular activity is influenced catalytically
Silicea (sillicic acid)
Weakness and impairment of the connective tissues; weakness of the ligaments
Nadide (nicotinamide adenine dinucleotide)
Coenzyme, stimulation of the end oxidation
in the respiratory chain
Coenzyme A (Coenzyme A)
Coenzyme for transacetylation
Thiotic acid
Coenzyme in the decomposition of pyruvic acid
Natrium oxalaceticum
Active factor of the citric acid cycle and of redox systems; sensitivity to damp and wind
For the maintenance of normal articular functions,
undisturbed co-ordination of the metabolism of the synovial membrane and synovial fluid on
the one hand and of the arthrodial cartilage on the other, is indispensable.
In the cartilage, according to the Embden-Meyerhof model, lactic acid or lactate is
formed, which reaches the outer cellular layer of the joint capsule through the synovial
fluid. There, by stimulation of the end oxidation through the citric acid cycle, the
necessary energy is released. In arthrosis, there is a pathological alteration of the
metabolism of the connective tissue in the joint (cartilage, synovial membrane and also
synovial fluid), characterized by increased degradation of the connective tissue
structures. This results, therefore, in disproportion between catabolic and anabolic
metabolic processes.
The task of effective therapy is to normalize the disturbed metabolism, as well as
offering components for possible incorporation.
The decisive energy-liberating reaction of the metabolism
is the formation of hydrogen, which is then transferred, to a great extent, to
nicotinamide adenine dinucleotide (nadid); thus, for example, the whole of the hydrogen
liberated in the course of the citric acid cycle is transferred to nadid, the starting
member of the respiratory chain. Precisely the oxidoreduction, catalysed by nadid, between
lactic acid and pyruvic acid, or the reverse, is of decisive importance in the metabolism
of the joints.
Thioctic acid is also a hydrogen-transferring co-factor
which, above all, participates decisively in the oxidative decarboxylation (conversion of
pyruvic acid to "activated acetic acid").
In the interaction with coenzyme A, the formation of the
"activated acetic acid") is made possible which, for its part, represents the
"initiator" of the citric acid cycle, while oxalacetate can be described as the
fuel, or also as the engine,of the citric acid cycle.
The treatment of rheumatic diseases with sulphur has long
been known. It is only through the biochemical research into mucopolysaccharide sulphates,
however, that it was confirmed, i.e. could be established, that the organism can
incorporate or convert the sulphur into chondroitin sulphates intrinsic to the body.
The organ constituents provide important components of the connective tissue (cartilage,
funiculus umbilicalis), while placenta promotes the circulation and the embryo has an
additional stimulating action.
The botanical constituents from Rhus toxicodendron,
Dulcamara, Sanguinaria, Symphytum and Arnica are applied for rheumatic diseases of the
joints, etc., including when the disorders are worsened in wet weather.
The medicaments blended into a pharmacologically active
and non-toxic combination in Zeel, on the basis of many years' medical experience and the
most recent biochemical research form a highly valuable remedy for chronic diseases of the
joints, as can be seen from the composition and from what has been confirmed by clinical
and practical tests.
Based on the individual homeopathic constituents of Zeel,
therapeutic possiblities result for the treatment of arthrosis (in particular
gonarthrosis), polyarthrosis, spondylarthrosis, periarthritis humeroscapularis.
The dosage is adjusted according to the disease, the clinical picture and the stage of the
illness:
1 tablet to be dissolved on the tongue 3-5 times daily.
1 ampule or, for the big
joints,
2 ampules on each occasion, s.c., intra-cutaneous, i.v., or periarticularly,
possibly paravertebrally.
The ointment should be applied or rubbed in morning and evening and, if necessary, more
often, at the affected areas, possibly using an ointment dressing.
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Tablets
$18.00
Ointment
$20.00
Oral Vials
$54.00
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