DESCRIPTION
Zinc 50 mg. Chelate tablets, offered by Nutrition
Dynamics, Inc., provide a significant amount of zinc, an essential mineral.
Absorbability of this formulation is enhanced by the chelation of zinc with
gluconic acid.
FUNCTIONS
Zinc is an essential trace element required for the
activity of over 300 enzymes and is involved in most major metabolic pathways.
Zinc participates not only in catalytic processes, but also in the structure
and stability of some regulatory proteins.
General signs of human zinc
deficiency indicate that zinc has important functions in maintaining immune
function, reproduction, healthy skin, and growth.
Numerous studies support the
fundamental role of zinc for normal immune response in humans. Immune cells
must be able to rapidly divide in order to respond to daily challenges. Like
all rapidly dividing cells, immune cells depend on adequate amounts of dietary
zinc.
As a cofactor
of the antioxidant enzyme superoxide dismutase (SOD), zinc can be considered an
antioxidant nutrient. Zinc supplementation has been shown to increase the
antioxidant activity of SOD, and provide increased free radical protection.
Zinc deficiency is associated with increased oxidative damage.
Absorption of toxic heavy metals,
especially cadmium and lead, is lower in individuals with high zinc status
compared to those with low zinc status.
The body pool of readily available
zinc appears to be small, which renders the body susceptible to deficiency and
therefore dependent on a steady dietary supply of bioavailable zinc. While
typical zinc intakes in U.S. adults are between 10 and 15 mg per day, which
approach the RDA, intakes in the elderly are often low. Pregnant women are also
at risk for zinc deficiency, since they have a higher requirement for this
trace element.
Frequently, vegetarians and
chronically depressed individuals have been found to have low zinc status.
INDICATIONS
Zinc 50 mg. Chelate may be a useful dietary adjunct
for those who wish to supplement their diet with a more bioavailable form of
zinc.
FORMULA (#7104)
Each Tablet Contains:
Zinc................................................... 50. mg
As present in 400 mg Zinc Gluconate in chelated
combination
SUGGESTED USE
Adults take 1 tablet daily or as directed by
physician.
SIDE EFFECTS
No adverse effects have been reported.
HOW SUPPLIED
Supplied in bottles of 100 tablets.
STORAGE
Store in a
cool, dry place, away from direct light. Keep out of reach of children.
REFERENCES
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leptin production in humans. Life Sci 2000;66:2143-9.
DiSilvestro, RA. Zinc in relation to diabetes and oxidative
disease. J Nutr 2000;130:1509S-11S.
Frederickson, CJ, Suh, SW, Silva, D, Thompson, RB.
Importance of zinc in the central nervous system: the zinc-containing neuron. J
Nutr 2000;130:1471S-83S.
Huang, X, Cuajungco, MP, Atwood, CS, Moir, RD, Tanzi, RE,
Bush, AI. Alzheimer's disease, beta-amyloid protein and zinc. J Nutr
2000;130:1488S-92S.
Kohn, S, Kohn, D, Schiller, D. Effect of zinc
supplementation on epidermal Langerhans' cells of elderly patients with
decubital ulcers. J Dermatol 2000;27:258-63.
MacDonald, RS. The role of zinc in growth and cell
proliferation. J Nutr 2000;130:1500S-8S.
McCall, KA, Huang, C, Fierke, CA. Function and mechanism of
zinc metalloenzymes. J Nutr 2000;130:1437S-46S.
Meynadier, J. Efficacy and safety study of two zinc
gluconate regimens in the treatment of inflammatory acne. Eur J Dermatol
2000;10:269-73.
Mocchegiani, E, Muzzioli, M, Giacconi, R. Zinc and
immunoresistance to infection in aging: new biological tools. Trends Pharmacol
Sci 2000;21:205-8.
Oteiza, PI, Clegg, MS, Zago, MP, Keen, CL. Zinc deficiency
induces oxidative stress and AP-1 activation in 3T3 cells. Free Radic Biol Med
2000;28:1091-9.
Powell, SR. The antioxidant properties of zinc. J Nutr
2000;130:1447S-54S.
These statements have not been evaluated by the Food and Drug
Administration.
This product is not intended to diagnose, treat, cure, or prevent any
disease.
Ó 2000 Douglas Laboratories, INC. All Rights
Reserved