Ayurvedic Herb Research -
Immunopharmacological studies on Picrorhiza kurroa
Royle-ex-Benth. Part IV:
Cellular mechanisms of anti-inflammatory action.
ABSTRACT:
In this work abrogation of
anti-inflammatory effect of Picrorhiza kurrora extract (PK) by beta-adrenergic
blockade was confirmed, which suggests alteration in cell-surface biology by PK treatment. Blockade of protein synthesis by
cycloheximide pretreatment reduced PK effect, suggesting protein mediation.
Metabolic
inhibitor dinitrophenol inhibited inflammatory cedema equally in control and PK treated animals, and masking of PK effect was concluded.
Discriminations of
anti-inflammatory mechanism(s) of PK and the latter two cytotoxic agents were inferred from
these observations and from existing knowledge.
Selective PK influence on membrane linked activation events in
inflammatory effector cells could be the basis of anti-inflammatory and perhaps other
biological activities reported with the herb Picrorhiza kurrora.
Pandy, B.L.; Das, P.K. Department of Pharmacology, Banaras Hindu University, Varanasi, India. J Physiol Pharmacol 1989 Jan-Mar;33(1):28-30. NLM CIT. ID:89291011
Index of Articles
Click Here
Signup • Lost
Password • Edit Profile
for any specific ingredient, concern, vitamin, herb, etc...
• Health Club • Home •
Vitamins • Herbs • Minerals • Amino Acids • Enzymes • Hormones
Homeopathics • Ayurveda • Glandulars • Fatty Acids • Xtra-Cell
• Natural Medicines • Library • Physicians Only
Read The Latest Health Research • Prescription Drug Support Formulas Frozen Cellular Extracts • Xtra-Cell • Top Products •
Contact Us • Customer Service • Privacy Policy • Conditions Of Use
Pricing, Availability and Returns • Privacy Companies
Development Team
Nutrition Dynamics, Inc.• 510 West Court Street • Seguin, Texas 78155
800.926.2906
Copyright © 1998-2008 • All Rights Reserved • Patent Pending